VISPRIL TABLETS

Name : Vispril Tablets

Vispril is an oral long-acting angiotensin-converting enzyme (ACE) inhibitor. Vispril is used to treat high blood pressure (hypertension), congestive heart failure, and to improve survival after a heart attack. COMPOSITION: Each uncoated tablet contains Lisinopril Dihydrate BP Eq. to Lisinopril 10 mg Excipients Q.S.

• To treat a condition known as symptomatic heart failure where the heart no longer pumps blood as effectively as it should
• To treat high blood pressure
• To help prevent any more heart problems in patients who have recently had a heart attack
• To treat kidney disease resulting from diabetes and high blood pressure.
• Lisinopril is recommended in children (above 6 years old) only for the treatment of high blood pressure (hypertension).

Name : Vispril Tablets

Vispril is an oral long-acting angiotensin converting enzyme (ACE) inhibitor. Vispril used to treat high blood pressure (hypertension), congestive heart failure, and to improve survival after a heart attack. Absorption Following oral administration of Vispril, peak serum concentrations occur within about 7 hours, although there was a trend to a small delay in time taken to reach peak serum concentrations in acute myocardial infarction patients. Based on urinary recovery, the mean extent of absorption of lisinopril is approximately 25% with inter-patient variability of 6-60% over the dose range studied (5-80mg). The absolute bioavailability is reduced approximately 16% in patients with heart failure. Lisinopril absorption is not affected by the presence of food. Lisinopril does not appear to be bound to serum proteins other than to circulating angiotensin converting enzyme (ACE). Studies in rats indicate that lisinopril crosses the blood-brain barrier poorly. Elimination: Lisinopril does not undergo metabolism and is excreted entirely unchanged into the urine. On multiple dosing lisinopril has an effective half-life of accumulation of 12.6 hours. The clearance of lisinopril in healthy subjects is approximately 50 ml/min.

• Hypersensitivity to the active substance or to any of the excipients or any other angiotensin converting enzyme (ACE) inhibitor.
• History of angioedema associated with previous ACE inhibitor therapy.
• Hereditary or idiopathic angioedema.
• SIDE-EFFECTS: Dizziness, Headache, Cough, Diarrhoea, Vomiting etc.
• DRUG INTERACTION: Lithium, Potassium Supplements, Diuretics.
• OVER DOSAGE Limited data are available for overdose in humans. The recommended treatment of overdose is intravenous infusion of normal saline solution.
• PRESENTATION: 1 x 10 tablets Alu-Alu in a Mono Pack.
• Store below 25˚C, Protect from light.
• KEEP OUT OF REACH OF CHILDREN.
• COMPOSITION: Each uncoated tablet contains: Lisinopril Dihydrate BP Eq. to Lisinopril 10 mg Excipients Q.S.