VISPRIL TABLETS

Name : VISPRIL TABLETS

Vispril is an oral long-acting angiotensin-converting enzyme (ACE) inhibitor. Vispril is used to treat high blood pressure (hypertension), congestive heart failure, and to improve survival after a heart attack. COMPOSITION: Each uncoated tablet contains Lisinopril Dihydrate BP Eq. to Lisinopril 10 mg Excipients Q.S.

• To treat a condition known as symptomatic heart failure where the heart no longer pumps blood as effectively as it should
• To help prevent any more heart problems in patients who have recently had a heart attack
• Lisinopril is recommended in children (above 6 years old) only for the treatment of high blood pressure (hypertension).
• To treat high blood pressure
• To treat kidney disease resulting from diabetes and high blood pressure.

Name : VISPRIL TABLETS

Vispril is an oral long-acting angiotensin converting enzyme (ACE) inhibitor. Vispril used to treat high blood pressure (hypertension), congestive heart failure, and to improve survival after a heart attack. Absorption Following oral administration of Vispril, peak serum concentrations occur within about 7 hours, although there was a trend to a small delay in time taken to reach peak serum concentrations in acute myocardial infarction patients. Based on urinary recovery, the mean extent of absorption of lisinopril is approximately 25% with inter-patient variability of 6-60% over the dose range studied (5-80mg). The absolute bioavailability is reduced approximately 16% in patients with heart failure. Lisinopril absorption is not affected by the presence of food. Lisinopril does not appear to be bound to serum proteins other than to circulating angiotensin converting enzyme (ACE). Studies in rats indicate that lisinopril crosses the blood-brain barrier poorly. Elimination: Lisinopril does not undergo metabolism and is excreted entirely unchanged into the urine. On multiple dosing lisinopril has an effective half-life of accumulation of 12.6 hours. The clearance of lisinopril in healthy subjects is approximately 50 ml/min.

• Hypersensitivity to the active substance or to any of the excipients or any other angiotensin converting enzyme (ACE) inhibitor.
• Hereditary or idiopathic angioedema.
• DRUG INTERACTION: Lithium, Potassium Supplements, Diuretics.
• PRESENTATION: 1 x 10 tablets Alu-Alu in a Mono Pack.
• KEEP OUT OF REACH OF CHILDREN.
• History of angioedema associated with previous ACE inhibitor therapy.
• SIDE-EFFECTS: Dizziness, Headache, Cough, Diarrhoea, Vomiting etc.
• OVER DOSAGE Limited data are available for overdose in humans. The recommended treatment of overdose is intravenous infusion of normal saline solution.
• Store below 25˚C, Protect from light.
• COMPOSITION: Each uncoated tablet contains: Lisinopril Dihydrate BP Eq. to Lisinopril 10 mg Excipients Q.S.